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EFFECTS OF PREOPERATIVE AORTIC INSUFFICIENCY ON OUTCOME FOLLOWING AORTIC VALVE SPARING SURGERY

de Kerchove Laurent, Boodhwani Munir, Glineur David, Poncelet Alain, Rubay Jean, Astarci Parla, Verhelst Robert, Lacroix Valérie, Van Dyck Michel, Vanoverschelde Jean-Louis, Noirhomme Philippe, El Khoury Gébrine

 

Cliniques Universitaires St-Luc, Bruxelles

Objectives: The presence of significant preoperative aortic insufficiency (AI) or the need for cusp repair has been suggested as a risk factor for poorer outcome following aortic valve (AV) sparing surgery. We analyzed the influence of those factors on the mid-term outcomes of aortic AV surgery.

Methods: Between 1996 and 2008, 164 consecutive patients underwent elective AV sparing surgery. Severe preoperative AI (grade≥3+) was present in 93 patients (57%) and 54 (33%) had a bicuspid valve. Root repair was performed with either the reimplantation (74%) or remodeling technique (26%) and cusp repair was performed in 90 patients (55%). Mean clinical follow-up was 57 months.

Results: Hospital mortality was 0.6%. Cusp repair was required in 52% of the patients with preoperative AI≤2+ and in 57% of those with AI≥3+ (p=0.6). Cusp repair was required more frequently in bicuspid versus tricuspid valves (91% vs. 38%, p<.001). Overall survival at 8 years was 88%. Freedom from aortic valve reoperation at 8 years was similar with preoperative AI≤2+ or with preoperative AI≥3+ (89% vs. 90%, p=0.7) and with or without cusp repair (84% vs. 92%, p=0.5). Freedom from recurrent AI (grade≥3+) at 5 years was also similar between groups (90% vs. 89%, p=0.9 and 90% vs. 89%, p=0.8 respectively). By multivariate analyzes, predictors of recurrent AI≥2+ were preoperative left ventricle end-diastolic diameter and AI>1+ on discharge echocardiography.

Conclusions: With a systematic approach to cusp assessment and repair, aortic valve sparing surgery for root pathology has an acceptable mid-term outcome, irrespective of preoperative aortic insufficiency or need for cusp repair.

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Last Modified: 5-Oct-2009
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