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COMPLETE THORACOSCOPIC PULMONARY VEIN ISOLATION WITH GANGLIONIC PLEXUS ABLATION AND LEFT ATRIAL APPENDAGE AMPUTATION FOR TREATMENT OF LONE ATRIAL FIBRILLATION

van der Schoot J.H.F.1, Geuzebroek G.S.C. 1, van Putte B.P.1, Boersma L.V.A.1, de Bakker J.M.T.2, van Boven W-J1, Yilmaz A1

 

1St Antonius Hospital, Nieuwegein, The Netherlands
2Academical Medical Centre Amsterdam, The Netherlands

Objectives: Percutaneous pulmonary vein isolation (PVI) is the treatment of choice for symptomatic, drug-refractory atrial fibrillation (AF). A minimally invasive surgical approach can, however, provide an attractive alternative. The objective of this study was to assess the feasibility, effectiveness and safety of a complete thoracoscopic procedure to cure AF.

Methods: A bilateral ‘video assisted thoracoscopy’ was used to isolate both sets of pulmonary veins with bipolar RF-energy, ablate ganglionic plexus (GP) and amputate the left atrial appendage. Preoperative, in-hospital and follow-up data were studied of our first 30 patients. Holter registration was available in 91% of the patients who had no registered relapse of AF.

Results: Forty-three percent of the patients had undergone a previous percutaneous PVI. AF was paroxysmal in 63%, persistent in 27% and permanent in 10%. Mean left atrial diameter was 42.1±7.4 mm and mean duration of AF was 79.0±63.9 months. During a mean follow-up of 11.6 months, freedom from AF was obtained in 77% of the patients. There was no significant difference in freedom from AF between patients with paroxysmal, persistent or permanent AF. All patients who had a history of percutaneous PVI were free from AF during follow-up. Complications consisted of a conversion to a sternotomy in 2 patients, because of bleeding and severe pleural adhesions. During follow-up no CVA’s or pacemaker implantation occurred and none of the patients died

Conclusions: A complete thoracoscopic PVI with GP ablation and amputation of the left atrial appendage is feasible, effective and safe for the treatment of lone AF.

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Last Modified: 12-Oct-2009
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