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A 10- year experience with Primary Closure for Sternal Wound Infection : Can we reduce In-hospital mortality ?

A.J. Poncelet, B. Lengele, B. Delaere, A. Lurquin, D. Glineur, Y. d’Udekem d’Acoz, R. Verhelst, J. Rubay, JC Funken, P. Astarci, G. El Khoury, Ph. Noirhomme

 

Cliniques Univ. Saint-Luc, Brussels

Objectives: To evalute a simple treatment algorithm in sternal wound infection (SWI) allowing for primary closure and to describe the different surgical techniques and their associated morbidity and mortality.

Methods: A retrospective analysis of all patients operated on between 1996 and 2004 in a single tertiary care institution.  All epidemiological and surgical data were prospectively collected in our database. Univariate and multivariate analysis was used to determine preoperative and peri-operative risks factors for overall mortality in SWI patients.

Results: Out of 5,905 procedures, 146 sternal wound infection (SWI) were documented (2.4%).  The respective incidence of SWI for CABG, isolated valve, or combined procedures were 2.8%, 1.1% and 3.3%.  Pathogens involved were S. Epidemidis ( 44.5%), S. Aureus (31.5%) and Gram negative rods (21.2%).  Re-operation was required in 130/146 patients.  Mean time to the first reintervention was 17.3 days (Std dev : 12 d). Modalities of treatment consisted of drainage alone (44 patients),  rewiring (25 patients),  rewiring and mediastinal lavage (52 patients), and partial/complete sternectomy (10 patients).  Additional procedures were required in 49 patients (37.7%).  The 90-day mortality for uninfected patients and patients with superficial SWI  was 4.4% and 5.5% (p=0.78). For patients with deep SWI, 90-d mortality was 14.5% (p< .0001).

Conclusions: Deep sternal wound infection (DSWI) remains a dreadful complication in contemporary cardiac surgery while risk factors are currently  well defined. Using a simple approach of primary closure together with liberal use of vascularized flaps has allowed us to  achieve satisfactory short-term outcome  in this subset of patients.

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Last Modified: 30-Sep-2006
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